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Homeopathy and Homotoxicology Research

The following are some examples of the latest research being conducted in Europe into the efficacy of Homotoxicology for treating a broad range of conditions.

Acute Lower Back Pain

A homeopathic gel Spiroflor SRL was shown to be effective in treating lower back pain. A multi-centre, randomised, double-blind comparative clinical trial was carried out at general practices in Bristol and Manchester, UK, to investigate the efficacy and safely of a homeopathic gel for treating acute lower back pain.  One hundred and sixty one participants were randomly given either a Homeopathic Spiroflor SRL gel or Cremor Capsici Compositium FNA ointment. Pain reduction was evaluated using a visual analogue scale, noting any adverse side effects.
Both medications were found to be equally effective, but the gel was better tolerated.

Stam C., et al. (2001). The efficacy and safety of a homeopathic gel in the treatment of acute low back pain: a multi-centre, randomised, double-blind comparative clinical trial. British Homeopathic Journal. (90):21-28.

Childhood Fevers

Viburcol N suppositories were found to be as effective as Paracetamol/Acetaminophen for the management of feverish infections in children.  767 children with acute feverish infection were treated with either Viburcol (n = 361) or Paracetamol/Acetaminophen (n = 406) for a period of 1-3 days. Both groups exhibited clinically relevant improvements in body temperature, malaise and severity of acute infection as evidenced by symptoms of restlessness and fever. In over 90% of cases, efficacy and tolerability were rated ‘good’ to ‘very good’. The study concluded Viburcol N suppositories is a safe and effective alternative in efficacy to Paracetamol/Acetaminophen.

Muller-Krampe et al. (2003). Symptomatic treatment of acute feverish infections with a modern Homeopathy medication. Biological Therapy. (3):6-11.


Homotoxicology-prepared plant extract was shown to increase cell proliferation of human cutaneous fibroblasts in vitro. According to Homotoxicology, illness is defined as an overload of the connective tissue matrix with toxic substances, the homotoxins. Fibroblasts are the local cells of this matrix and produce and modulate the composition of the extra cellular matrix (ECM) in every organ. In order to support elimination of the homotoxins from the connective tissue matrix, complex homeopathic medicines were developed.  A study carried out at the Institute for Anatomy II, University Hamburg-Eppendorf, Germany, investigated the effect of 17 potentiated plant extracts, which are components of some antihomotoxic remedies, on the cell proliferation of human cutaneous fibroblasts (F54).  Cell proliferation of the F54 cells was measured by a colorimetric XTT-based assay kit.  Six of the tested agents had no effect on the cell proliferation of fibroblasts; 11 plant extracts had a dose-dependent inhibitory effect on cell proliferation. The authors concluded that the plant extracts might modulate the composition of the ECM via the inhibitory effect on fibroblast cell growth.

Valentiner U. et al (2003). Effect of homeopathic plant extract on cell proliferation on fibroblasts in vitro. Forsch Komplementarmed Klass Naturheilkd. 122-7.


Zeel compositum N was found to be as effective as COX 2 inhibitors in treating osteoarthritis. From 592 participants with mild osteoarthritis of the knee, 323 received Zeel comp. N and 269 received either Celecoxib or Rofecoxib. Both treatments showed equivalent efficacy after 6 weeks. However, Zeel comp. N had significantly higher tolerability than the COC 2 inhibitors, producing superior overall treatment outcome by reducing costs related to management of adverse side effects and improving compliance, making it a treatment of preference.

Birnesser H et al. 2003. A modern Homeoapthic medication works as well as COX 2 inhibitors.  Der Allgemeinarzt. (4);261-264.


Atropa Belladonna and Echinacea Angustifolia in homeopathic dilution were shown to be effective on peritonitis.
A study carried out at the Faculty of Health Sciences of Sao Paulo, IBEHE, Brazil, evaluated the effects of these homeopathic agents on leukocyte migration and macrophage activity induced by experimental peritonitis in vivo. Mice were injected with LPS (1.0mg/kg) and treated (0.3ml/10g/day) with different commercial forms of these medicines. Echinacea angustifolia D4 and Belladonna Homaccord, Belladonna Injeel, Belladonna Injeel Forte, Echinacea Injeel and Echinacea Injeel Forte were used in accord potencies. The combination of A. belladonna and E. angustifolia in 'accord of potencies' produced an increase of polymorphonuclear cell migration and a decrease of mononuclear cell percentages, when compared with control, mainly in preparations containing low potencies. The proportion of degenerate leukocytes was lower in the treated groups, compared to a control group. The treated groups showed increased phagocytosis, mainly in preparations containing high potencies. The results suggest that A. belladonna and E. angustifolia, when prepared in 'accord of potencies', modulate peritoneal inflammatory reaction and have a cytoprotective action on leukocytes.

Pedalino CM. (2006) Effect of Atropa belladonna and Echinacea angustifolia in homeopathic dilution on experimental peritonitis. Homeopathy.93(4):193-8.


Traumeel was showed to be effective in reducing symptoms of chemotherapy-induced Stomatitis in children. Thirty-two participants were randomly assigned to receive either Traumeel or placebo for a month. The symptoms were scored using World Health Organisation (WHO) mucositis scale.  Traumeel group showed significant reduction in symptoms, scoring 10.4 compared with 24.3 for the placebo group. The authors concluded that the frequency and severity of chemotherapy-induced Stomatitis could be significantly reduced by administrating Traumeel.
Oberbaum M et al. (2001). A randomised Controlled Clinical trial of the Homeopathic Medication Traumeel S in the treatment of Chemotherapy-induced Stomatitis in Children undergoing stem cell transplantation. Cancer. 92(2):684-690


Vertigoheel has been shown to be as effective as Dimenhydrinate for treating nonvestibular vertigo.  One hundred and ninety eight participants, randomly selected from a population of 774 patients, received either (91 participants) or Dimenhydrinate (107 participants). 80% of participants in Vertigoheel group reported ‘good’ to ‘very good’ results in treating the vertigo and associated nausea.

Strosser W,. er al. (2001). Vertigoheel (Tablet) vs. Dimenhydrinate (50mg Tablet) bei der Behandlung von nicht-vestibularem schwindel. Bilogical Medicine. 31 (1):4